Research Data from Charles University Update Understanding of Biomedical Engineering.

According to the authors of recent research from Prague, Czech Republic, "Several groups found different impact of erythropoietin (EPO) on liver regeneration. Both proproliferative as well as anti-proliferative and non-proliferative activities have been reported using high dosage of EPO."

"Systemic administration of high doses of this cytokine is a clinical concern due to risk of thrombosis. Herein, we applied EPO in low dosages and investigated whether it can stimulate liver regeneration after liver resection. Main methods: Parameters of liver regeneration were assessed 3 days after 70% hepatectomy by means of immunochemistry and proteomics. EPO was given twice in low dosages …